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A Computational Approach to Analyze the Mechanism of Action of the Kinase Inhibitor Bafetinib

Prediction of drug action in human cells is a major challenge in biomedical research. Additionally, there is strong interest in finding new applications for approved drugs and identifying potential side effects. We present a computational strategy to predict mechanisms, risks and potential new domai...

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Detalles Bibliográficos
Autores principales: Burkard, Thomas R., Rix, Uwe, Breitwieser, Florian P., Superti-Furga, Giulio, Colinge, Jacques
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987840/
https://www.ncbi.nlm.nih.gov/pubmed/21124949
http://dx.doi.org/10.1371/journal.pcbi.1001001