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A Computational Approach to Analyze the Mechanism of Action of the Kinase Inhibitor Bafetinib
Prediction of drug action in human cells is a major challenge in biomedical research. Additionally, there is strong interest in finding new applications for approved drugs and identifying potential side effects. We present a computational strategy to predict mechanisms, risks and potential new domai...
Autores principales: | Burkard, Thomas R., Rix, Uwe, Breitwieser, Florian P., Superti-Furga, Giulio, Colinge, Jacques |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987840/ https://www.ncbi.nlm.nih.gov/pubmed/21124949 http://dx.doi.org/10.1371/journal.pcbi.1001001 |
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