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SECRET domain of variola virus CrmB protein can be a member of poxviral type II chemokine-binding proteins family

BACKGROUND: Variola virus (VARV) the causative agent of smallpox, eradicated in 1980, have wide spectrum of immunomodulatory proteins to evade host immunity. Recently additional biological activity was discovered for VARV CrmB protein, known to bind and inhibit tumour necrosis factor (TNF) through i...

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Detalles Bibliográficos
Autores principales: Antonets, Denis V, Nepomnyashchikh, Tatyana S, Shchelkunov, Sergei N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987869/
https://www.ncbi.nlm.nih.gov/pubmed/20979600
http://dx.doi.org/10.1186/1756-0500-3-271