Thermodynamic modeling of transcription: sensitivity analysis differentiates biological mechanism from mathematical model-induced effects

BACKGROUND: Quantitative models of gene expression generate parameter values that can shed light on biological features such as transcription factor activity, cooperativity, and local effects of repressors. An important element in such investigations is sensitivity analysis, which determines how str...

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Detalles Bibliográficos
Autores principales: Dresch, Jacqueline M, Liu, Xiaozhou, Arnosti, David N, Ay, Ahmet
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987881/
https://www.ncbi.nlm.nih.gov/pubmed/20969803
http://dx.doi.org/10.1186/1752-0509-4-142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987881/
https://www.ncbi.nlm.nih.gov/pubmed/20969803
http://dx.doi.org/10.1186/1752-0509-4-142

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