Mcm10 proteolysis initiates before the onset of M-phase

BACKGROUND: Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubiquitinates Mcm10 in late M and early G(1 )phases. RESUL...

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Detalles Bibliográficos
Autores principales: Kaur, Manpreet, Sharma, Aparna, Khan, Muntaz, Kar, Ananya, Saxena, Sandeep
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987893/
https://www.ncbi.nlm.nih.gov/pubmed/20979666
http://dx.doi.org/10.1186/1471-2121-11-84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987893/
https://www.ncbi.nlm.nih.gov/pubmed/20979666
http://dx.doi.org/10.1186/1471-2121-11-84

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