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Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic Pulmonary Fibrosis (IPF) is an unresolved clinical issue. Phosphodiesterases (PDEs) are known therapeutic targets for various proliferative lung diseases. Lung PDE6 expression and function has received little or no attention. The present study aimed to characterize (i) PDE6 su...

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Detalles Bibliográficos
Autores principales: Nikolova, Sevdalina, Guenther, Andreas, Savai, Rajkumar, Weissmann, Norbert, Ghofrani, Hossein A, Konigshoff, Melanie, Eickelberg, Oliver, Klepetko, Walter, Voswinckel, Robert, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T, Pullamsetti, Soni S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988012/
https://www.ncbi.nlm.nih.gov/pubmed/20979602
http://dx.doi.org/10.1186/1465-9921-11-146