Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients

BACKGROUND: The spike (S) protein of SARS-CoV not only mediates receptor-binding but also induces neutralizing antibodies. We previously identified the receptor-binding domain (RBD) of S protein as a major target of neutralizing antibodies in animal models and thus proposed a RBD-based vaccine. Howe...

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Detalles Bibliográficos
Autores principales: Cao, Zhiliang, Liu, Lifeng, Du, Lanying, Zhang, Chao, Jiang, Shibo, Li, Taisheng, He, Yuxian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988023/
https://www.ncbi.nlm.nih.gov/pubmed/21047436
http://dx.doi.org/10.1186/1743-422X-7-299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988023/
https://www.ncbi.nlm.nih.gov/pubmed/21047436
http://dx.doi.org/10.1186/1743-422X-7-299

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