Anti-CD4-mediated selection of Treg in vitro – in vitro suppression does not predict in vivo capacity to prevent graft rejection

Regulatory T cells (Treg) have been shown to play a role in the prevention of autoimmune diseases and transplant rejection. Based on an established protocol known to generate alloantigen reactive Treg in vivo, we have developed a strategy for the in vitro selection of Treg. Stimulation of unfraction...

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Detalles Bibliográficos
Autores principales: Oliveira, Vanessa, Sawitzki, Birgit, Chapman, Stephanie, Appelt, Christine, Gebuhr, Inga, Wieckiewicz, Joanna, Long, Elaine, Wood, Kathryn J
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2008
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988420/
https://www.ncbi.nlm.nih.gov/pubmed/18465768
http://dx.doi.org/10.1002/eji.200737562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988420/
https://www.ncbi.nlm.nih.gov/pubmed/18465768
http://dx.doi.org/10.1002/eji.200737562

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