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Anti-CD4-mediated selection of Treg in vitro – in vitro suppression does not predict in vivo capacity to prevent graft rejection

Regulatory T cells (Treg) have been shown to play a role in the prevention of autoimmune diseases and transplant rejection. Based on an established protocol known to generate alloantigen reactive Treg in vivo, we have developed a strategy for the in vitro selection of Treg. Stimulation of unfraction...

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Detalles Bibliográficos
Autores principales:	Oliveira, Vanessa, Sawitzki, Birgit, Chapman, Stephanie, Appelt, Christine, Gebuhr, Inga, Wieckiewicz, Joanna, Long, Elaine, Wood, Kathryn J
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2008
Materias:	Immunomodulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988420/ https://www.ncbi.nlm.nih.gov/pubmed/18465768 http://dx.doi.org/10.1002/eji.200737562

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