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Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell Non-Hodgkin’s Lymphoma: Results of the FAB/LMB 96 international study

Clinical studies showed that advanced stage, high LDH, poor response to reduction therapy and combined bone marrow and central nervous system disease are significantly associated with a decreased event free survival (EFS) in pediatric mature B-NHL treated on FAB/LMB96. Although rearranged MYC/8q24 (...

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Detalles Bibliográficos
Autores principales: Poirel, HA, Cairo, MS, Heerema, NA, Swansbury, J, Aupérin, A, Launay, E, Sanger, WG, Talley, P, Perkins, SL, Raphaël, M, McCarthy, K, Sposto, R, Gerrard, M, Bernheim, A, Patte, C
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988438/
https://www.ncbi.nlm.nih.gov/pubmed/19020548
http://dx.doi.org/10.1038/leu.2008.312