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Broker Genes in Human Disease

Genes that underlie human disease are important subjects of systems biology research. In the present study, we demonstrate that Mendelian and complex disease genes have distinct and consistent protein–protein interaction (PPI) properties. We show that five different network properties can be reduced...

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Detalles Bibliográficos
Autores principales: Cai, James J., Borenstein, Elhanan, Petrov, Dmitri A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988523/
https://www.ncbi.nlm.nih.gov/pubmed/20937604
http://dx.doi.org/10.1093/gbe/evq064