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A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples

BACKGROUND: We have compared mutation analysis by DNA sequencing and Amplification Refractory Mutation System™ (ARMS™) for their ability to detect mutations in clinical biopsy specimens. METHODS: We have evaluated five real-time ARMS assays: BRAF 1799T>A, [this includes V600E and V600K] and NRAS...

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Detalles Bibliográficos
Autores principales: Ellison, Gillian, Donald, Emma, McWalter, Gael, Knight, Lucy, Fletcher, Lynn, Sherwood, James, Cantarini, Mireille, Orr, Maria, Speake, Georgina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988723/
https://www.ncbi.nlm.nih.gov/pubmed/20925915
http://dx.doi.org/10.1186/1756-9966-29-132