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Aminopeptidases do not directly degrade tau protein

BACKGROUND: Tau hyperphosphorylation and aggregation to form intracellular neurofibrillar tangles is prevalent in a number of tauopathies. Thus there is current interest in the mechanisms involved in Tau clearance. It was recently reported that Tau can be degraded by an aminopeptidase known as the p...

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Detalles Bibliográficos
Autores principales: Chow, K Martin, Guan, Hanjun, Hersh, Louis B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988785/
https://www.ncbi.nlm.nih.gov/pubmed/21054848
http://dx.doi.org/10.1186/1750-1326-5-48