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Structural basis for cooperative RNA binding and export complex assembly by HIV Rev
HIV replication requires nuclear export of unspliced viral RNAs to translate structural proteins and package genomic RNA. Export is mediated by cooperative binding of the Rev protein to the Rev response element (RRE) RNA, forming a highly specific oligomeric ribonucleoprotein (RNP) that binds to the...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988976/ https://www.ncbi.nlm.nih.gov/pubmed/20953181 http://dx.doi.org/10.1038/nsmb.1902 |