Cargando…

Visualizing the transfer-messenger RNA as the ribosome resumes translation

Bacterial ribosomes stalled by truncated mRNAs are rescued by transfer-messenger RNA (tmRNA), a dual-function molecule that contains a tRNA-like domain (TLD) and an internal open reading frame (ORF). Occupying the empty A site with its TLD, the tmRNA enters the ribosome with the help of elongation f...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Jie, Hashem, Yaser, Wower, Iwona, Lei, Jianlin, Liao, Hstau Y, Zwieb, Christian, Wower, Jacek, Frank, Joachim
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989109/
https://www.ncbi.nlm.nih.gov/pubmed/20940705
http://dx.doi.org/10.1038/emboj.2010.255