Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation

BACKGROUND: Transactive response DNA-binding protein 43 (TDP-43) is the pathological protein found in frontotemporal lobar degeneration with ubiquitin positive inclusions and in amyotrophic lateral sclerosis. In diseased tissue, TDP-43 translocates from its physiological nuclear location into the cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Caccamo, Antonella, Magrí, Andrea, Oddo, Salvatore
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989316/
https://www.ncbi.nlm.nih.gov/pubmed/21070634
http://dx.doi.org/10.1186/1750-1326-5-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989316/
https://www.ncbi.nlm.nih.gov/pubmed/21070634
http://dx.doi.org/10.1186/1750-1326-5-51

Ejemplares similares