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ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

Carbohydrate responsive element-binding protein (ChREBP) is a transcription factor whose expression and activity are increased in pancreatic β-cells maintained at elevated glucose concentrations. We show here that ChREBP inactivation in clonal pancreatic MIN6 β-cells results in an increase in Pdx-1...

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Detalles Bibliográficos
Autores principales: da Silva Xavier, Gabriela, Sun, Gao, Qian, Qingwen, Rutter, Guy A., Leclerc, Isabelle
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989445/
https://www.ncbi.nlm.nih.gov/pubmed/20934404
http://dx.doi.org/10.1016/j.bbrc.2010.10.010