Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice

Abnormalities in expression levels of the IgG inhibitory Fc gamma receptor IIB (FcγRIIB) are associated with the development of immunoglobulin (Ig) G serum autoantibodies and systemic autoimmunity in mice and humans. We used Ig gene cloning from single isolated B cells to examine the checkpoints tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Tiller, Thomas, Kofer, Juliane, Kreschel, Cornelia, Busse, Christian E., Riebel, Stefan, Wickert, Susanne, Oden, Felix, Mertes, Maria M.M., Ehlers, Marc, Wardemann, Hedda
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989760/
https://www.ncbi.nlm.nih.gov/pubmed/21078890
http://dx.doi.org/10.1084/jem.20100171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989760/
https://www.ncbi.nlm.nih.gov/pubmed/21078890
http://dx.doi.org/10.1084/jem.20100171

Ejemplares similares