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Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse

The immune synapse (IS) forms as dendritic cells (DCs) and T cells interact in lymph nodes during initiation of adaptive immunity. Factors that contribute to the formation and maintenance of IS stability and function have been mostly studied in T cells, whereas little is known about events occurring...

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Detalles Bibliográficos
Autores principales: Pulecio, Julian, Petrovic, Jelena, Prete, Francesca, Chiaruttini, Giulia, Lennon-Dumenil, Ana-Maria, Desdouets, Chantal, Gasman, Stephane, Burrone, Oscar R., Benvenuti, Federica
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989776/
https://www.ncbi.nlm.nih.gov/pubmed/21059854
http://dx.doi.org/10.1084/jem.20100007