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Cdc42-mediated MTOC polarization in dendritic cells controls targeted delivery of cytokines at the immune synapse
The immune synapse (IS) forms as dendritic cells (DCs) and T cells interact in lymph nodes during initiation of adaptive immunity. Factors that contribute to the formation and maintenance of IS stability and function have been mostly studied in T cells, whereas little is known about events occurring...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989776/ https://www.ncbi.nlm.nih.gov/pubmed/21059854 http://dx.doi.org/10.1084/jem.20100007 |