A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2

Spinal muscular atrophy (SMA) is a neurological disorder characterized by motor neuron degeneration and progressive muscle paralysis. The disease is caused by a reduction in survival of motor neuron (SMN) protein resulting from homozygous deletion of the SMN1 gene. SMN protein is also encoded by SMN...

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Detalles Bibliográficos
Autores principales: Jodelka, Francine M., Ebert, Allison D., Duelli, Dominik M., Hastings, Michelle L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989896/
https://www.ncbi.nlm.nih.gov/pubmed/20884664
http://dx.doi.org/10.1093/hmg/ddq425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989896/
https://www.ncbi.nlm.nih.gov/pubmed/20884664
http://dx.doi.org/10.1093/hmg/ddq425

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