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Dopamine Transporter Binding Is Unaffected by L-DOPA Administration in Normal and MPTP-Treated Monkeys

BACKGROUND: Radiotracer imaging of the presynaptic nigrostriatal dopaminergic system is used to assess disease progression in Parkinson's disease (PD) and may provide a useful adjunct to clinical assessment during therapeutic trials of potential neuroprotective agents. Several clinical trials c...

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Detalles Bibliográficos
Autores principales: Fernagut, Pierre-Olivier, Li, Qin, Dovero, Sandra, Chan, Piu, Wu, Tao, Ravenscroft, Paula, Hill, Michael, Chen, Zhenwen, Bezard, Erwan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989907/
https://www.ncbi.nlm.nih.gov/pubmed/21124922
http://dx.doi.org/10.1371/journal.pone.0014053