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T. gondii RP Promoters & Knockdown Reveal Molecular Pathways Associated with Proliferation and Cell-Cycle Arrest

Molecular pathways regulating rapid proliferation and persistence are fundamental for pathogens but are not elucidated fully in Toxoplasma gondii. Promoters of T. gondii ribosomal proteins (RPs) were analyzed by EMSAs and ChIP. One RP promoter domain, known to bind an Apetela 2, bound to nuclear ext...

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Detalles Bibliográficos
Autores principales: Hutson, Samuel L., Mui, Ernest, Kinsley, Karen, Witola, William H., Behnke, Michael S., El Bissati, Kamal, Muench, Stephen P., Rohrman, Brittany, Liu, Susan R., Wollmann, Robert, Ogata, Yuko, Sarkeshik, Ali, Yates, John R., McLeod, Rima
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989910/
https://www.ncbi.nlm.nih.gov/pubmed/21124925
http://dx.doi.org/10.1371/journal.pone.0014057