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Ectopic T Cell Receptor-α Locus Control Region Activity in B Cells Is Suppressed by Direct Linkage to Two Flanking Genes at Once

The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα LCR DNA supports a gene expression pattern th...

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Detalles Bibliográficos
Autores principales: Knirr, Stefan, Gomos-Klein, Janette, Andino, Blanca E., Harrow, Faith, Erhard, Karl F., Kovalovsky, Damian, Sant'Angelo, Derek B., Ortiz, Benjamin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989920/
https://www.ncbi.nlm.nih.gov/pubmed/21124935
http://dx.doi.org/10.1371/journal.pone.0015527