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Ectopic T Cell Receptor-α Locus Control Region Activity in B Cells Is Suppressed by Direct Linkage to Two Flanking Genes at Once
The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα LCR DNA supports a gene expression pattern th...
Autores principales: | Knirr, Stefan, Gomos-Klein, Janette, Andino, Blanca E., Harrow, Faith, Erhard, Karl F., Kovalovsky, Damian, Sant'Angelo, Derek B., Ortiz, Benjamin D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989920/ https://www.ncbi.nlm.nih.gov/pubmed/21124935 http://dx.doi.org/10.1371/journal.pone.0015527 |
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