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Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

BACKGROUND: Epithelial cell adhesion molecule (EpCAM) is frequently and highly expressed on human carcinomas. The emerging role of EpCAM as a signalling receptor and activator of the wnt pathway, and its expression on tumor-initiating cells, further add to its attractiveness as target for immunother...

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Detalles Bibliográficos
Autores principales: Münz, Markus, Murr, Alexander, Kvesic, Majk, Rau, Doris, Mangold, Susanne, Pflanz, Stefan, Lumsden, John, Volkland, Jörg, Fagerberg, Jan, Riethmüller, Gert, Rüttinger, Dominik, Kufer, Peter, Baeuerle, Patrick A, Raum, Tobias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989956/
https://www.ncbi.nlm.nih.gov/pubmed/21044305
http://dx.doi.org/10.1186/1475-2867-10-44