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Loss of Octarepeats in Two Processed Prion Pseudogenes in the Red Squirrel, Sciurus vulgaris

The N-terminal region of the mammalian prion protein (PrP) contains an ‘octapeptide’ repeat which is involved in copper binding. This eight- or nine-residue peptide is repeated four to seven times, depending on the species, and polymorphisms in repeat number do occur. Alleles with three repeats are...

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Detalles Bibliográficos
Autores principales: Madsen, Ole, Kortum, Timothy T., Hupkes, Marlinda, Kohlen, Wouter, van Rheede, Teun, de Jong, Wilfried W.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990005/
https://www.ncbi.nlm.nih.gov/pubmed/20878152
http://dx.doi.org/10.1007/s00239-010-9390-7