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Analytical Validation of a Highly Quantitative, Sensitive, Accurate, and Reproducible Assay (HERmark(®)) for the Measurement of HER2 Total Protein and HER2 Homodimers in FFPE Breast Cancer Tumor Specimens

We report here the results of the analytical validation of assays that measure HER2 total protein (H2T) and HER2 homodimer (H2D) expression in Formalin Fixed Paraffin Embedded (FFPE) breast cancer tumors as well as cell line controls. The assays are based on the VeraTag technology platform and are c...

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Detalles Bibliográficos
Autores principales: Larson, Jeffrey S., Goodman, Laurie J., Tan, Yuping, Defazio-Eli, Lisa, Paquet, Agnes C., Cook, Jennifer W., Rivera, Amber, Frankson, Kristi, Bose, Jolly, Chen, Lili, Cheung, Judy, Shi, Yining, Irwin, Sarah, Kiss, Linda D. B., Huang, Weidong, Utter, Shannon, Sherwood, Thomas, Bates, Michael, Weidler, Jodi, Parry, Gordon, Winslow, John, Petropoulos, Christos J., Whitcomb, Jeannette M.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990097/
https://www.ncbi.nlm.nih.gov/pubmed/21151530
http://dx.doi.org/10.4061/2010/814176