Cargando…

Spindle checkpoint silencing: ensuring rapid and concerted anaphase onset

The spindle checkpoint delays anaphase onset in the presence of defective kinetochore-microtubule attachments. Such delays can last for just a few minutes or several hours, but very shortly after all chromosomes achieve bi-orientation, a remarkably synchronous anaphase ensues. We are beginning to un...

Descripción completa

Detalles Bibliográficos
Autores principales: Hardwick, Kevin G, Shah, Jagesh V
Formato: Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990540/
https://www.ncbi.nlm.nih.gov/pubmed/21173869
http://dx.doi.org/10.3410/B2-55