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Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies

BACKGROUND: Insulin-like growth factor-binding protein 7 (IGFBP7) is an abundant, selective and accessible biomarker of glioblastoma multiforme (GBM) tumour vessels. In this study, an anti-IGFBP7 single-domain antibody (sdAb) was developed to target GBM vessels for molecular imaging applications. ME...

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Detalles Bibliográficos
Autores principales: Iqbal, U, Albaghdadi, H, Luo, Y, Arbabi, M, Desvaux, C, Veres, T, Stanimirovic, D, Abulrob, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990581/
https://www.ncbi.nlm.nih.gov/pubmed/20959824
http://dx.doi.org/10.1038/sj.bjc.6605937