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MicroRNA-21 induces resistance to the anti-tumour effect of interferon-α/5-fluorouracil in hepatocellular carcinoma cells

BACKGROUND: We reported recently the clinical efficiency of interferon (IFN)-α/5-fluorouracil (5-FU) combination therapy in advanced hepatocellular carcinoma (HCC). However, prediction of the response to the combination therapy remains unsatisfactory. The aim of this study was to investigate the ant...

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Detalles Bibliográficos
Autores principales: Tomimaru, Y, Eguchi, H, Nagano, H, Wada, H, Tomokuni, A, Kobayashi, S, Marubashi, S, Takeda, Y, Tanemura, M, Umeshita, K, Doki, Y, Mori, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990590/
https://www.ncbi.nlm.nih.gov/pubmed/20978511
http://dx.doi.org/10.1038/sj.bjc.6605958