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Role of human tissue kallikrein in gastrointestinal stromal tumour invasion

BACKGROUND: Human tissue kallikrein (hK1) generates vasodilator kinins from kininogen and promotes angiogenesis by kinin-dependent and kinin-independent mechanisms. Here, we investigate the expression and functional relevance of hK1 in human gastrointestinal stromal tumour (GIST). METHODS: Vasculari...

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Detalles Bibliográficos
Autores principales: Dominek, P, Campagnolo, P, H-Zadeh, M, Kränkel, N, Chilosi, M, Sharman, J A, Caporali, A, Mangialardi, G, Spinetti, G, Emanueli, C, Pignatelli, M, Madeddu, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990601/
https://www.ncbi.nlm.nih.gov/pubmed/20859288
http://dx.doi.org/10.1038/sj.bjc.6605906