Combination of sapacitabine and HDAC inhibitors stimulates cell death in AML and other tumour types

BACKGROUND: Alternative treatments are needed for elderly patients with acute myeloid leukaemia, as the disease prognosis is poor and the current treatment is unsuitable for many patients. METHODS: In this study, we investigated whether combining the nucleoside analogue sapacitabine with histone dea...

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Detalles Bibliográficos
Autores principales: Green, S R, Choudhary, A K, Fleming, I N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990608/
https://www.ncbi.nlm.nih.gov/pubmed/20924380
http://dx.doi.org/10.1038/sj.bjc.6605922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990608/
https://www.ncbi.nlm.nih.gov/pubmed/20924380
http://dx.doi.org/10.1038/sj.bjc.6605922

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