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A pilot study on the immunogenicity of dendritic cell vaccination during adjuvant oxaliplatin/capecitabine chemotherapy in colon cancer patients

BACKGROUND: Dendritic cell (DC) vaccination has been shown to induce anti-tumour immune responses in cancer patients, but so far its clinical efficacy is limited. Recent evidence supports an immunogenic effect of cytotoxic chemotherapy. Pre-clinical data indicate that the combination of chemotherapy...

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Detalles Bibliográficos
Autores principales: Lesterhuis, W J, de Vries, I J M, Aarntzen, E A, de Boer, A, Scharenborg, N M, van de Rakt, M, van Spronsen, D-J, Preijers, F W, Figdor, C G, Adema, G J, Punt, C J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990614/
https://www.ncbi.nlm.nih.gov/pubmed/20924373
http://dx.doi.org/10.1038/sj.bjc.6605935