Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-(13)C]pyruvate and [1,4-(13)C(2)]fumarate

BACKGROUND: The recent introduction of a dynamic nuclear polarisation technique has permitted noninvasive imaging of tumour cell metabolism in vivo following intravenous administration of (13)C-labelled cell substrates. METHODS: Changes in hyperpolarised [1-(13)C]pyruvate and [1,4-(13)C(2)]fumarate...

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Detalles Bibliográficos
Autores principales: Witney, T H, Kettunen, M I, Hu, D-e, Gallagher, F A, Bohndiek, S E, Napolitano, R, Brindle, K M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990617/
https://www.ncbi.nlm.nih.gov/pubmed/20924379
http://dx.doi.org/10.1038/sj.bjc.6605945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990617/
https://www.ncbi.nlm.nih.gov/pubmed/20924379
http://dx.doi.org/10.1038/sj.bjc.6605945

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