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Impact of translational error-induced and error-free misfolding on the rate of protein evolution

What determines the rate of protein evolution is a fundamental question in biology. Recent genomic studies revealed a surprisingly strong anticorrelation between the expression level of a protein and its rate of sequence evolution. This observation is currently explained by the translational robustn...

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Detalles Bibliográficos
Autores principales: Yang, Jian-Rong, Zhuang, Shi-Mei, Zhang, Jianzhi
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990641/
https://www.ncbi.nlm.nih.gov/pubmed/20959819
http://dx.doi.org/10.1038/msb.2010.78