Cargando…

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway

Oxidized glutathione (GSSG) is commonly viewed as a byproduct of GSH metabolism. The pathophysiological significance of GSSG per se remains poorly understood. Adopting a microinjection approach to isolate GSSG elevation within the cell, this work identifies that GSSG can trigger neural HT4 cell deat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Han-A, Khanna, Savita, Rink, Cameron, Gnyawali, Surya, Roy, Sashwati, Sen, Chandan K.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990696/ https://www.ncbi.nlm.nih.gov/pubmed/19373248 http://dx.doi.org/10.1038/cdd.2009.37

Ejemplares similares

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
por: Gnyawali, Surya C., et al.
Publicado: (2010)

Retooling Laser Speckle Contrast Analysis Algorithm to Enhance Non-Invasive High Resolution Laser Speckle Functional Imaging of Cutaneous Microcirculation
por: Gnyawali, Surya C., et al.
Publicado: (2017)

Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD(+) and SIRT1
por: Ghosh, Nandini, et al.
Publicado: (2020)

Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction
por: Roy, Sashwati, et al.
Publicado: (2013)

Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain
por: Palakurti, Ravichand, et al.
Publicado: (2023)

Supplementation of a Standardized Extract from Phyllanthus emblica Improves Cardiovascular Risk Factors and Platelet Aggregation in Overweight/Class-1 Obese Adults
por: Khanna, Savita, et al.
Publicado: (2015)

A surfactant polymer wound dressing protects human keratinocytes from inducible necroptosis
por: Khandelwal, Puneet, et al.
Publicado: (2021)

High resolution ultrasound imaging for repeated measure of wound tissue morphometry, biomechanics and hemodynamics under fetal, adult and diabetic conditions
por: Gnyawali, Surya C., et al.
Publicado: (2020)

Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion
por: Drefs, Moritz, et al.
Publicado: (2017)

Moisture mitigation using a vented liner and a vented socket system for individuals with transfemoral amputation
por: Gnyawali, Surya C., et al.
Publicado: (2023)

A Modified Collagen Dressing Induces Transition of Inflammatory to Reparative Phenotype of Wound Macrophages
por: Das, Amitava, et al.
Publicado: (2019)

Robust critical limb ischemia porcine model involving skeletal muscle necrosis
por: El Masry, Mohamed S., et al.
Publicado: (2023)

Glutathione disulfide liposomes – A research tool for the study of glutathione disulfide associated functions and dysfunctions
por: Sadhu, Satya S., et al.
Publicado: (2016)

Photoperiodic Regulation of Cerebral Blood Flow in White-Footed Mice (Peromyscus leucopus)
por: Borniger, Jeremy C., et al.
Publicado: (2016)

Novel mechanisms of Collagenase Santyl Ointment (CSO) in wound macrophage polarization and resolution of wound inflammation
por: Das, Amitava, et al.
Publicado: (2018)

High-Resolution Harmonics Ultrasound Imaging for Non-Invasive Characterization of Wound Healing in a Pre-Clinical Swine Model
por: Gnyawali, Surya C., et al.
Publicado: (2015)

Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice
por: Khanna, Savita, et al.
Publicado: (2010)

Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue
por: Sinha, Mithun, et al.
Publicado: (2018)

Glutathione Peroxide and Glutathione to Disulfide Glutathione Ratio in Presbycusis: a Case-control Study
por: Hasansulama, Wijana, et al.
Publicado: (2022)

Silver-Zinc Redox-Coupled Electroceutical Wound Dressing Disrupts Bacterial Biofilm
por: Banerjee, Jaideep, et al.
Publicado: (2015)

Chronic Arsenic Exposure and Blood Glutathione and Glutathione Disulfide Concentrations in Bangladeshi Adults
por: Hall, Megan N., et al.
Publicado: (2013)

Collagen in Wound Healing
por: Mathew-Steiner, Shomita S., et al.
Publicado: (2021)

Electroceutical fabric lowers zeta potential and eradicates coronavirus infectivity upon contact
por: Ghatak, Subhadip, et al.
Publicado: (2021)

Reduced glutathione and glutathione disulfide in the blood of glucose-6-phosphate dehydrogenase-deficient newborns
por: Gong, Zhen-hua, et al.
Publicado: (2017)

In Vitro and In Vivo Antimetastatic Effect of Glutathione Disulfide Liposomes
por: Sadhu, Satya S, et al.
Publicado: (2017)

Regulation of Tissue Inflammation by 12-Lipoxygenases
por: Kulkarni, Abhishek, et al.
Publicado: (2021)

AutoMated Burn Diagnostic System for Healthcare (AMBUSH)
por: Masry, Mohamed El, et al.
Publicado: (2023)

Targeting Persister Hyperbiofilm Forming Bacterial Infection: The GelATA Wound Care Dressing
por: El Masry, Mohamed Salah, et al.
Publicado: (2022)

In Vitro and In Vivo Tumor Growth Inhibition by Glutathione Disulfide Liposomes
por: Sadhu, Satya S, et al.
Publicado: (2017)

Improvement of Human Keratinocyte Migration by a Redox Active Bioelectric Dressing
por: Banerjee, Jaideep, et al.
Publicado: (2014)

Novel Bacterial Diversity and Fragmented eDNA Identified in Hyperbiofilm-Forming Pseudomonas aeruginosa Rugose Small Colony Variant
por: Deng, Binbin, et al.
Publicado: (2020)

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
por: Xu, Ronald X., et al.
Publicado: (2010)

Nutrigenomic Analysis of Diet-Gene Interactions on Functional Supplements for Weight Management
por: Lau, Francis C, et al.
Publicado: (2008)

Senescence-associated tumor growth is promoted by 12-Lipoxygenase
por: Patil, Shilpa, et al.
Publicado: (2022)

Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization
por: Soria-Tiedemann, Mariana, et al.
Publicado: (2022)

A surfactant polymer dressing potentiates antimicrobial efficacy in biofilm disruption
por: Das Ghatak, Piya, et al.
Publicado: (2018)

Pseudomonas Aeruginosa Theft Biofilm Require Host Lipids of Cutaneous Wound
por: Sinha, Mithun, et al.
Publicado: (2023)

Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS
por: Sun, Xueni, et al.
Publicado: (2020)

Emerging Roles of 5-Lipoxygenase Phosphorylation in Inflammation and Cell Death
por: Sun, Qian-Yi, et al.
Publicado: (2019)

Engineering Smut Resistance in Maize by Site-Directed Mutagenesis of LIPOXYGENASE 3
por: Pathi, Krishna Mohan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g6oi8ao09jek2l0rt586hf1bso