The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation

Activation of the mammalian Notch receptor after ligand binding relies on a succession of events including metalloprotease-cleavage, endocytosis, monoubiquitination, and eventually processing by the gamma-secretase, giving rise to a soluble, transcriptionally active molecule. The Notch1 receptor was...

Descripción completa

Detalles Bibliográficos
Autores principales: Moretti, Julien, Chastagner, Patricia, Gastaldello, Stefano, Heuss, Sara F., Dirac, Annette M., Bernards, René, Masucci, Maria G., Israël, Alain, Brou, Christel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990700/
https://www.ncbi.nlm.nih.gov/pubmed/21124883
http://dx.doi.org/10.1371/journal.pbio.1000545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990700/
https://www.ncbi.nlm.nih.gov/pubmed/21124883
http://dx.doi.org/10.1371/journal.pbio.1000545

Ejemplares similares