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The Biphasic Increase of PIP2 in the Fertilized Eggs of Starfish: New Roles in Actin Polymerization and Ca(2+) Signaling

BACKGROUND: Fertilization of echinoderm eggs is accompanied by dynamic changes of the actin cytoskeleton and by a drastic increase of cytosolic Ca(2+). Since the plasma membrane-enriched phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) serves as the precursor of inositol 1,4,5 trisphosphate...

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Detalles Bibliográficos
Autores principales: Chun, Jong T., Puppo, Agostina, Vasilev, Filip, Gragnaniello, Giovanni, Garante, Ezio, Santella, Luigia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990714/
https://www.ncbi.nlm.nih.gov/pubmed/21124897
http://dx.doi.org/10.1371/journal.pone.0014100