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Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study
BACKGROUND: Histamine-metabolizing enzymes (N-methyltransferase and amiloride binding protein 1) are responsible for histamine degradation, a biogenic amine involved in allergic inflammation. Genetic variants of HNMT and ABP1 genes were found to be associated with altered enzyme activity. We hypothe...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990726/ https://www.ncbi.nlm.nih.gov/pubmed/21040557 http://dx.doi.org/10.1186/1476-7961-8-14 |