An integrated approach to epitope analysis I: Dimensional reduction, visualization and prediction of MHC binding using amino acid principal components and regression approaches

BACKGROUND: Operation of the immune system is multivariate. Reduction of the dimensionality is essential to facilitate understanding of this complex biological system. One multi-dimensional facet of the immune system is the binding of epitopes to the MHC-I and MHC-II molecules by diverse populations...

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Detalles Bibliográficos
Autores principales: Bremel, Robert D, Homan, E Jane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990731/
https://www.ncbi.nlm.nih.gov/pubmed/21044289
http://dx.doi.org/10.1186/1745-7580-6-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990731/
https://www.ncbi.nlm.nih.gov/pubmed/21044289
http://dx.doi.org/10.1186/1745-7580-6-7

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