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Numerical optimization of gene electrotransfer into muscle tissue

BACKGROUND: Electroporation-based gene therapy and DNA vaccination are promising medical applications that depend on transfer of pDNA into target tissues with use of electric pulses. Gene electrotransfer efficiency depends on electrode configuration and electric pulse parameters, which determine the...

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Detalles Bibliográficos
Autores principales: Zupanic, Anze, Corovic, Selma, Miklavcic, Damijan, Pavlin, Mojca
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990758/
https://www.ncbi.nlm.nih.gov/pubmed/21050435
http://dx.doi.org/10.1186/1475-925X-9-66