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Evolution of Allosteric Citrate Binding Sites on 6-phosphofructo-1-kinase
As an important part of metabolism, metabolic flux through the glycolytic pathway is tightly regulated. The most complex control is exerted on 6-phosphofructo-1-kinase (PFK1) level; this control overrules the regulatory role of other allosteric enzymes. Among other effectors, citrate has been report...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990764/ https://www.ncbi.nlm.nih.gov/pubmed/21124851 http://dx.doi.org/10.1371/journal.pone.0015447 |