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Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair

INTRODUCTION: In this study, we investigate the efficacy of repairing an osteochondral defect in rabbit knee joints by administering bevacizumab, a humanized monoclonal anti-vascular endothelial growth factor (VEGF) antibody. METHODS: An osteochondral defect was created on the patellar groove of 20...

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Detalles Bibliográficos
Autores principales: Nagai, Toshihiro, Sato, Masato, Kutsuna, Toshiharu, Kokubo, Mami, Ebihara, Goro, Ohta, Naoshi, Mochida, Joji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991009/
https://www.ncbi.nlm.nih.gov/pubmed/20868495
http://dx.doi.org/10.1186/ar3142