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The effect of immunomodulators on the immunogenicity of TNF-blocking therapeutic monoclonal antibodies: a review

Therapeutic monoclonal antibodies have revolutionized the treatment of various inflammatory diseases. Immunogenicity against these antibodies has been shown to be clinically important: it is associated with shorter response duration because of diminishing concentrations in the blood and with infusio...

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Detalles Bibliográficos
Autores principales: Krieckaert, Charlotte Louise Maria, Bartelds, Geertje Margret, Lems, Willem Frederik, Wolbink, Gerrit Jan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991013/
https://www.ncbi.nlm.nih.gov/pubmed/21029481
http://dx.doi.org/10.1186/ar3147