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Simultaneous Genome-Wide Inference of Physical, Genetic, Regulatory, and Functional Pathway Components

Biomolecular pathways are built from diverse types of pairwise interactions, ranging from physical protein-protein interactions and modifications to indirect regulatory relationships. One goal of systems biology is to bridge three aspects of this complexity: the growing body of high-throughput data...

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Detalles Bibliográficos
Autores principales: Park, Christopher Y., Hess, David C., Huttenhower, Curtis, Troyanskaya, Olga G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991250/
https://www.ncbi.nlm.nih.gov/pubmed/21124865
http://dx.doi.org/10.1371/journal.pcbi.1001009