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Treatment-Mediated Alterations in HIV Fitness Preserve CD4(+) T Cell Counts but Have Minimal Effects on Viral Load

For most HIV-infected patients, antiretroviral therapy controls viral replication. However, in some patients drug resistance can cause therapy to fail. Nonetheless, continued therapy with a failing regimen can preserve or even lead to increases in CD4(+) T cell counts. To understand the biological b...

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Detalles Bibliográficos
Autores principales: Vaidya, Naveen K., Rong, Libin, Marconi, Vincent C., Kuritzkes, Daniel R., Deeks, Steven G., Perelson, Alan S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991251/
https://www.ncbi.nlm.nih.gov/pubmed/21124866
http://dx.doi.org/10.1371/journal.pcbi.1001012