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Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

Two-component signal transduction systems enable bacteria to sense and respond to a wide range of environmental stimuli. Sensor histidine kinases transmit signals to their cognate response regulators via phosphorylation. The faithful transmission of information through two-component pathways and the...

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Detalles Bibliográficos
Autores principales: Capra, Emily J., Perchuk, Barrett S., Lubin, Emma A., Ashenberg, Orr, Skerker, Jeffrey M., Laub, Michael T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991266/
https://www.ncbi.nlm.nih.gov/pubmed/21124821
http://dx.doi.org/10.1371/journal.pgen.1001220