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Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways
Two-component signal transduction systems enable bacteria to sense and respond to a wide range of environmental stimuli. Sensor histidine kinases transmit signals to their cognate response regulators via phosphorylation. The faithful transmission of information through two-component pathways and the...
Autores principales: | Capra, Emily J., Perchuk, Barrett S., Lubin, Emma A., Ashenberg, Orr, Skerker, Jeffrey M., Laub, Michael T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991266/ https://www.ncbi.nlm.nih.gov/pubmed/21124821 http://dx.doi.org/10.1371/journal.pgen.1001220 |
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