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CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Genomic imprints—parental allele-specific DNA methylation marks at the differentially methylated regions (DMRs) of imprinted genes—are erased and reestablished in germ cells according to the individual's sex. Imprint establishment at paternally methylated germ line DMRs occurs in fetal male ger...

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Detalles Bibliográficos
Autores principales: Lee, Dong-Hoon, Singh, Purnima, Tsai, Shirley Y., Oates, Nathan, Spalla, Alexander, Spalla, Claudio, Brown, Lucy, Rivas, Guillermo, Larson, Garrett, Rauch, Tibor A., Pfeifer, Gerd P., Szabó, Piroska E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991272/
https://www.ncbi.nlm.nih.gov/pubmed/21124827
http://dx.doi.org/10.1371/journal.pgen.1001224